CAS 66852-01-5 Tyrosylleucine TFA

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CAS 66852-01-5 Tyrosylleucine TFA
Detalls
CAS: 66852-01-5
Core structure: Natural dipeptide composed of L-tyrosine and L-leucine, TFA purification intermediate form, with both antioxidant and skin repair activities, commonly used as skincare active ingredient and peptide synthesis intermediate
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Small-molecule Active Dipeptide / Skincare Raw Material Intermediate
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CAS:66852‑01‑5:Tyrosylleucine TFA
Tyrosylleucine (Tyr‑Leu) is a simple natural dipeptide. It exerts free radical scavenging and antioxidant effects through the phenolic hydroxyl group of tyrosine, and can alleviate oxidative stress damage to cells; meanwhile, it has mild skin repair activity and can improve skin barrier status. The trifluoroacetate salt is an intermediate salt form during HPLC purification, with good water solubility. It can be used as skincare active ingredient, peptide synthesis building block and biological research control reagent.
95%/98%/99%
C₁₅H₂₂N₂O₄
294.34, higher for TFA salt form

 

 

Function Tags (comma-separated)
Tyrosylleucine TFA; Tyr-Leu TFA Tyrosine-leucine linear dipeptide, composed of native amino acids 294.16 294.34 2

 

 

Long-term Storage Short-term Storage
PEP-TYL001 White to off-white crystalline powder Store at -20℃, sealed, dry & protected from light, aliquoted; avoid repeated freeze-thaw cycles and strong oxidizing environment Stable for 1 month at 2-8℃ sealed & dry; ice pack shipping recommended Stable for 7 days at 4℃; phenolic hydroxyl group prone to slow oxidation at room temperature,**Excellent water solubility, freely soluble in water, alcohols and physiological buffer**. Small-molecule dipeptide with strong permeability Stable for 2 years at -20℃ under dry & dark conditions

 

 

Applicable Research Areas (comma-separated)
PEP-TYL001 The antioxidant activity of tyrosylleucine mainly comes from the phenolic hydroxyl group of tyrosine residue. It can directly scavenge reactive oxygen species such as hydroxyl radicals and superoxide anions through hydrogen donation, reduce cell lipid peroxidation and protein damage caused by oxidative stress, and exert mild antioxidant protective effect. Its dipeptide structure has small molecular weight and can easily penetrate the skin stratum corneum, exerting local skin repair and barrier improvement effects. The dipeptide has mild activity, no strong pharmacological toxicity, and high safety, suitable for use as skincare raw material, synthesis intermediate and control reagent.

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